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Aclidinium (Bretaris Genuair) for chronic obstructive pulmonary ...
Aclidinium (Bretaris Genuair) for chronic obstructive pulmonary ...
Aug 1, 2014 ... Aclidinium bromide is a long-acting anticholinergic (or long-acting ... antagonist) with efficacy and safety similar to those of tiotropium...

The PBAC accepted the proposed price for aclidinium bromide. The listing of aclidinium bromide was estimated to result in a total net saving to the PBS/RPBS of between $10 and $30 million over the first five years, due to the predicted substitution only from tiotropium and the lower DPMQ of aclidinium bromide compared to tiotropium. Efficacy and safety of twice-daily aclidinium bromide in COPD patients: the ATTAIN study.

Although the incidence of cardiac adverse events was low, the PBAC noted that the European Medicines Agency lists aclidinium bromide as a medicinal product under additional monitoring to closely monitor for cardiovascular effects. AUC = area under the curve; COPD = chronic obstructive pulmonary disease; DB=double blind; DD = double dummy; FEV = Forced expiratory volume in one second; FVC = forced vital capacity; MC = multi centre; MD = multiple dose; N = number in trial; PC = placebo controlled; R = randomised; SGRQ = St George’s respiratory questionnaire; wks = weeks; yrs = years The PBAC noted that no consumer comments were received for this item. The fixed-dose combinations of fluticasone–salmeterol and budesonide–eformoterol are combinations of glucocorticoids with LABAs, used as long-acting bronchodilators in severe COPD, and either may be used concurrently with aclidinium for severe COPD. Beier J, Kirsten AM, Mroz R, et al. The submission presented a cost-minimisation analysis using a comparison of drug costs only.

inhalers bretaris genuair and COPD | MyCOPDTeam
bretaris genuair ... The inhalers that I have are Tiotropium 18 microgram once a day, seretide 500 ... Is there a generic for Anoro Ellipta, or a cheaper alternative? bretaris vs spiriva generic Pharmaceutical Benefits Scheme (PBS) | ACLIDINIUM BROMIDE ...Mar 25, 2014 ... Efficacy and safety of aclidinium bromide at two dose levels vs. placebo ... Tiotropium versus placebo for chronic obstructive pulmonary disease. Aclidinium bromide - WikipediaAclidinium bromide (INN) is a long-acting, inhaled muscarinic antagonist (LAMA) approved in ... It is unclear if it differs from the similar medication tiotropium or other commonly used medications from the class of LAMAs. ... licensed to Menarini under the brand name Bretaris Genuair for majority of EU member states.
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